Squamous Cell Carcinoma Antigen (SCC) Test – Cost, Purpose and How It Works

Reviewed by Dr Lauren Holland • Marylebone Diagnostic Centre
Results within 24–42 hours. Westminster residents receive 20% off – BOOK NOW

The Squamous Cell Carcinoma Antigen (SCC) blood test is a tumour-associated marker that can support the assessment and monitoring of certain cancers, particularly those involving squamous cells. Clinically, SCC antigen levels may be raised in cancers of the cervix, head and neck, lung, oesophagus and skin. The test is sometimes requested by clinicians for monitoring, follow-up or when investigating persistent symptoms that warrant a deeper clinical picture.

This guide explains what the SCC test measures, how it works, who may need it, the test’s limitations, and how to book a private SCC antigen blood test at Marylebone Diagnostic Centre in central London. It also includes typical pricing, result timelines and frequently asked questions.

What Is the Squamous Cell Carcinoma Antigen (SCC) Test?

SCC antigen is a protein produced by squamous cells.
Blood levels may be elevated when these cells become abnormal or undergo malignant change.

What the SCC test measures

The blood test provides a numerical value of SCC antigen.
Higher levels may be associated with:

• Cervical squamous cell carcinoma
• Head and neck squamous cell carcinoma
• Lung squamous cell carcinoma
• Oesophageal squamous cell carcinoma
• Certain skin cancers (less commonly)

It is not a diagnostic test on its own.
Instead, SCC antigen is used as a supporting marker alongside imaging, histology and clinical assessment.

How the SCC Test Works

Step 1 – Blood sample

A small venous blood sample is taken at the clinic.

Step 2 – Laboratory analysis

The sample is analysed using high-sensitivity immunoassay methods that quantify the amount of SCC antigen.

Step 3 – Interpretation

Results are reviewed by a clinician and interpreted in the context of:

• Medical history
• Symptoms
• Imaging reports
• Previous SCC antigen results
• Relevant clinical findings

Step 4 – Next steps

A high or rising SCC antigen level may prompt further investigation, but it does not diagnose cancer by itself.

At Marylebone Diagnostic Centre, results are reviewed by our Medic for clarity and accuracy.

Who May Need an SCC Antigen Test?

SCC testing may be useful for individuals who:

• Are being monitored for known squamous cell carcinoma
• Require follow-up after treatment
• Have persistent or unexplained symptoms
• Have been advised by a clinician to check SCC levels
• Require trend monitoring over time
• Want private access to tumour-associated marker testing

Symptoms that may prompt clinicians to request SCC testing

(Not diagnostic, but may lead to further evaluation)

• Persistent throat pain
• Long-standing cough
• Unexplained weight loss
• Abnormal cervical findings
• Long-lasting skin lesions
• Difficulty swallowing
• Persistent hoarseness
• Unusual lumps in the neck or throat
• Abnormal bleeding (cervical conditions)

A clinician must evaluate results within the appropriate clinical context.

What SCC Antigen Levels Can Indicate

Normal or low SCC levels

These can be reassuring but do not rule out disease on their own.

Elevated SCC levels

May indicate:

• Tumour presence
• Tumour recurrence
• Treatment response when monitored over time
• Need for further clinical investigation

SCC is most useful when measured serially, as changes over time provide more insight.

SCC Antigen Test Cost in London (MDC Pricing)

Marylebone Diagnostic Centre offers competitive pricing:

SCC Antigen Blood Test

Price: £128 – BOOK NOW
Discount: Westminster residents receive 20% off

If you wish, I can prepare a formal pricing table for your website.

How Fast Are Results?

Most SCC antigen results are ready within:

✔ 24 – 42 hours

Results include:

• SCC antigen level
• Reference range
• Consultant review
• Next-step guidance if further assessment is recommended

How Accurate Is the SCC Antigen Test?

SCC is a supportive marker, meaning:

• It is not used for primary diagnosis
• It is more valuable when monitored over time
• It may rise for reasons other than cancer, including:
  • Inflammation
  • Skin conditions (eczema, psoriasis)
  • Respiratory infections
  • Kidney conditions

Therefore, it is interpreted alongside clinical findings, imaging and specialist review.

Why Choose Marylebone Diagnostic Centre?

• Fast results: 24–42 hours
• Central location: 73 Baker Street
• Five-minute walk from Baker Street Tube
• Medic-reviewed reports
• Private suites
• Strict quality control under the Marylebone High Standard
• Discreet and confidential
• Open Monday–Saturday
• Westminster residents receive 20% off

Clinically, patients often value timely reassurance and clear interpretation when tumour markers are involved.

How to Prepare for the SCC Antigen Test

• No fasting required
• Continue medication unless advised otherwise
• Hydrate well before your appointment
• Bring previous SCC results if available

Tracking changes over time helps clinicians understand the overall pattern.

FAQs

1. What is the SCC antigen test used for?

It measures squamous cell carcinoma antigen levels to support monitoring and clinical assessment.

2. Can the SCC test diagnose cancer on its own?

No. It is a supportive marker and must be interpreted with other investigations.

3. How quickly are results available?

Most results are returned within 24–42 hours.

4. How much does the SCC test cost?

Please refer to the clinic’s latest pricing. Westminster residents receive 20% off.

5. Why might SCC levels be elevated?

They may rise due to tumour activity, inflammation, skin conditions or respiratory issues.

6. Do I need to fast for the SCC test?

No. Fasting is not required.

7. Is this test useful for monitoring treatment?

Yes. Clinicians often track SCC levels over time to assess response.

8. What happens if my SCC level is high?

Your clinician may recommend further investigations or specialised imaging.

Book Your SCC Antigen Test at Marylebone Diagnostic Centre

Marylebone Diagnostic Centre
73 Baker Street, London W1U 6RD
Tel: +44 7495 970109
Open Monday–Saturday, 08:00–16:00

Fast, private and confidential SCC antigen testing with results in 24–42 hours.
Westminster residents receive 20% off all tests.