DAO Enzyme Test – What You Need to Know
MDC & Laboratory
Unexplained rashes, headaches, digestive discomfort, or fatigue can be frustrating. For some people, these symptoms may be linked to histamine intolerance. One key test for this condition is the DAO enzyme test. But what exactly is DAO, and how does the test work?
At Marylebone Diagnostic Centre, 73 Baker Street, London, we provide accurate DAO enzyme testing with same-day results. Here is everything you need to know.
What is DAO?
DAO stands for diamine oxidase, an enzyme produced in the intestines. Its job is to break down histamine, a chemical found in certain foods and released during immune responses.
When DAO levels are too low, histamine builds up in the body. This can lead to symptoms similar to allergies, even when no allergy is present.
What is histamine intolerance?
Histamine intolerance is not a classic allergy. Instead, it happens when your body cannot process histamine properly.
Common symptoms include:
- Headaches or migraines
- Hives, rashes, or flushing
- Stomach pain, bloating, or diarrhoea
- Runny nose or congestion
- Fatigue and brain fog
Symptoms may vary from mild to severe and often appear after eating certain foods.
Why is DAO important?
DAO is the main enzyme responsible for breaking down histamine in food. If your DAO activity is low, histamine can trigger unpleasant reactions.
Testing DAO levels helps identify whether histamine intolerance could explain ongoing, unexplained symptoms.
The DAO enzyme test
A DAO enzyme test is a simple blood test. It measures the level of DAO activity in your blood. Low levels suggest reduced ability to process histamine.
At MDC, the process is quick:
- Book your appointment online or by phone.
- Have your blood taken by our experienced team.
- Samples are tested using advanced technology.
- Same-day results are provided in most cases.
- Doctors explain findings and suggest next steps.
Who should consider a DAO enzyme test?
You may benefit from testing if you have:
- Unexplained allergy-like symptoms
- Headaches or migraines linked to food
- Digestive discomfort without a clear cause
- Rashes, flushing, or itching after meals
- Fatigue that worsens after certain foods
Testing is especially useful if traditional allergy tests are negative but symptoms persist.
How do doctors use DAO results?
Low DAO activity does not confirm histamine intolerance on its own. Instead, it guides further assessment.
Doctors may recommend:
- Dietary changes to reduce histamine-rich foods
- Lifestyle adjustments to lower triggers
- Additional tests to rule out other conditions
Combining test results with a clear symptom history gives the best picture.
Foods high in histamine
Some foods naturally contain more histamine. If DAO activity is low, these foods may cause stronger reactions:
- Aged cheese
- Red wine
- Cured meats
- Fermented foods (sauerkraut, soy sauce)
- Vinegar-based products
- Some fish such as tuna or mackerel
Reducing these foods can improve symptoms in many patients.
FAQs about DAO enzyme testing
The DAO enzyme test is a valuable tool for uncovering hidden causes of persistent symptoms. By checking your body’s ability to break down histamine, it helps guide dietary and lifestyle changes that can make a real difference.
At Marylebone Diagnostic Centre, 73 Baker Street, London, we provide fast and accurate DAO enzyme testing with expert follow-up advice. If you suffer from unexplained symptoms, this test could provide the answers you need.
Book your DAO enzyme test today at Marylebone Diagnostic Centre. Same-day results, trusted care, central London location.
73 Baker Street, London
+44 7495 970109
marylebonediagnosticcentre.com
