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How Often Should You Have a Smear Test in the UK?

Reviewed by Dr Lauren Holland • Marylebone Diagnostic Centre
Results within 24–42 hours. Westminster residents receive 20% off.

Note: MDC offers women’s health panels, HPV blood tests, STI blood tests, fertility panels and general health checks.

Smear tests (cervical screening) are one of the most effective ways to prevent cervical cancer. Many women, however, remain unsure about how often they need one, when they should start, and whether screening changes with age, symptoms or sexual activity. This guide explains UK recommendations, who needs screening, what results mean, and how Marylebone Diagnostic Centre supports women with complementary tests such as HPV blood tests, STI panels and hormone profiles.

How Often Should You Have a Smear Test?

According to UK cervical screening guidelines:

  • Age 25–49: Every 3 years
  • Age 50–64: Every 5 years
  • Over 65: Only if recent results were abnormal

Before age 25

Smear tests are not recommended because cervical cell changes are rare in this age group.

Who Needs More Frequent Testing?

Some women may require earlier or additional screening:

  • history of abnormal smears
  • HPV-positive results
  • immune system conditions
  • HIV-positive status
  • previous cervical treatment
  • symptoms such as bleeding after sex

MDC offers blood tests relevant to these risk factors.

Symptoms That Need Further Assessment

Even between smear tests, you should seek medical review if you have:

  • bleeding after intercourse
  • bleeding between periods
  • foul-smelling discharge
  • pelvic pain
  • pain during sex
  • unexplained spotting

These symptoms may require STI testing, inflammation markers or pelvic infection screening.

Understanding the Smear Test and HPV

Modern screening focuses on detecting high-risk HPV strains that cause cervical cancer. Early detection allows for preventive treatment.

Associated blood tests at MDC

  • HPV antibody tests
  • Full STI screening
  • CRP for inflammation
  • General women’s health panels

These support complete assessment.

What Happens if Results Are Abnormal?

Abnormalities do not mean cancer. Most are temporary HPV infections or mild cell changes.

Possible outcomes:

  • Repeat smear in 12 months
  • Colposcopy referral
  • Monitoring only

MDC can provide supportive testing while awaiting follow-up.

Complementary Tests Available at MDC

Full STI Panel
Useful when symptoms overlap with smear-related changes or unexplained pelvic discomfort.
Advanced Sexual Health Panel
Includes chlamydia, gonorrhoea, mycoplasma, ureaplasma and other key infections.
Hormone Profile
Helpful for irregular cycles, spotting, cramps or cycle-related pelvic symptoms.
HPV Antibody Blood Test
Assesses past exposure and immunity, especially useful when reviewing smear results.
Vitamin D & Iron
Fatigue, pelvic discomfort and low mood are often linked to deficiencies in these nutrients.

Why Women Delay Smear Tests

Common reasons:

  • fear of discomfort
  • embarrassment
  • uncertainty about timing
  • misconception that smear tests check all STIs
  • confusion after receiving the HPV vaccine

Clear information helps encourage screening.

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FAQs

How often should you have a smear test?
Every 3 years between the ages of 25 and 49, and every 5 years from 50 to 64.
Can you have a smear test earlier?
Only if you have symptoms or you’re under specialist care.
Does smear testing check for STIs?
No. Smear tests do not check for infections. You’ll need separate STI or HPV tests.
Can smear tests prevent cancer?
They detect early cell changes that can be treated before cancer develops.
Should you test if you had the HPV vaccine?
Yes. The vaccine doesn’t protect against all HPV strains, so screening is still important.

Book Women’s Health Testing at Marylebone Diagnostic Centre

Marylebone Diagnostic Centre
73 Baker Street, London W1U 6RD
Tel: +44 7495 970109

Fast, private and confidential women’s health testing with results in 24–42 hours.

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