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Inflammatory Markers – What CRP and ESR Reveal About Your Health

By Tharb Faisl

What Are Inflammatory Markers? Inflammation is your body’s natural response to injury, infection, or chronic illness — but when it becomes persistent or excessive, it may signal underlying disease.

Two of the most important blood tests for inflammation are:

  • CRP (C-Reactive Protein)
  • ESR (Erythrocyte Sedimentation Rate)

These tests help detect hidden inflammation even when symptoms seem vague or unexplained — such as chronic fatigue, joint pain, or autoimmune flare-ups.

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What’s the Difference Between CRP and ESR?

TestWhat It MeasuresWhy It’s Useful
CRPA protein produced by the liver in response to inflammationDetects early or acute inflammation, infection, and autoimmune activity
ESRThe rate at which red blood cells settle in a test tubeIndicates chronic inflammation or long-standing disease activity

They are often ordered together to give a broader picture of inflammatory health.

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When Should You Get a CRP or ESR Test?

Consider booking an inflammation screen if you have:

  • Persistent fatigue or malaise
  • Joint or muscle pain
  • Unexplained fevers
  • Autoimmune conditions (e.g., rheumatoid arthritis, lupus)
  • Ongoing infections or recovery from illness
  • Monitoring of inflammatory disorders or treatment effectiveness
  • General wellness screening when symptoms are unclear

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What’s Included at Marylebone Diagnostic Centre?

Often included in our Cardiac Profile, Well Person, and Fatigue Panels
Combine with: FBC, Vitamin D, B12, Thyroid Function, Iron Profile

Marylebone Diagnostic Centre Front

Located near Baker Street, with easy access from Marylebone, Paddington, Harley Street, Kings Cross, and Euston.

Why Testing Inflammation Matters

Chronic inflammation is linked to a wide range of conditions, including:

  • Heart disease
  • Type 2 diabetes
  • Autoimmune disorders
  • Long-term fatigue
  • Depression and cognitive changes
  • Digestive conditions like IBS or IBD

Catching and tracking inflammation early allows for quicker treatment and better outcomes.

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Real Patient Insight

“I felt off for months — tired, joint pain, just not myself. My CRP was sky-high. The Marylebone team helped me identify the source of the problem and get the treatment I needed.”
– Hannah, 42, Harley Street

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FAQs – CRP and ESR Testing

Do I need to fast for these tests?
No fasting is required.
Can they diagnose a disease on their own?
Not directly — they indicate inflammation and should be interpreted with other results.
Are these tests suitable for fatigue screening?
Yes — many patients with unexplained fatigue benefit from checking inflammation markers.
How quickly are results returned?
Typically within 24 hours.

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Book Your Inflammation Blood Test Today

Find answers to long-standing symptoms. Our trusted team at Marylebone Diagnostic Centre is ready to help.

✔️ Same-day appointments
✔️ Quick, accurate results
✔️ Supportive aftercare

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Learn More:

NHS – CRP Test
Patient.info – ESR Test