Zika Symptoms vs Dengue – How to Tell the Difference (London Guide 2026)

Zika vs Dengue – Key Symptom Differences

Zika Symptoms

Zika is usually milder and often overlooked.

• Mild fever 
• Maculopapular rash (very common) 
• Red eyes (conjunctivitis) 
• Joint pain (hands and feet) 
• Headache 
• Often no symptoms at all 

Zika is particularly important to detect in pregnancy.

Dengue Symptoms

Dengue tends to be more severe.

• High fever (often sudden onset) 
• Severe headache 
• Pain behind the eyes 
• Muscle and joint pain (“breakbone fever”) 
• Nausea and vomiting 
• Skin rash (appears later) 
• In severe cases: bleeding, low platelets 

Dengue can become life-threatening if untreated.

Zika vs Dengue – Quick Comparison Table

When Should You Get Tested in London?

You should consider testing if you:

• Recently travelled to tropical or endemic regions 
• Have fever, rash, or joint pain 
• Are pregnant or planning pregnancy 
• Feel unwell after returning to the UK 

Many infections are missed without laboratory testing.

Which Test Do You Need? 

Timing is everything:

Within 16 Days of Symptoms

 PCR testing is required
Detects active virus (Zika or Dengue)

After 15 Days

Antibody testing (IgM & IgG)
Detects immune response

Choosing the wrong test can lead to false reassurance or missed diagnosis

Zika Testing in London – What We Offer

At Marylebone Diagnostic Centre:

Zika PCR Test (Urine)

• Detects active infection 
• Best within first 14 days 
• Highly accurate 

Zika Antibody Test

• Detects past or recent infection 
• Ideal after 2 weeks 

Book your Zika test here:
https://www.marylebonediagnosticcentre.com/services/

Do You Also Need Dengue Testing?

Yes — in many cases, clinicians recommend testing for:

• Dengue virus 
• Other travel-related infections 

This is because symptoms overlap significantly.

MDC can guide you on combined testing panels for accurate diagnosis.

Why Choose Marylebone Diagnostic Centre

• Central London location (Baker Street) 
• Fast turnaround times 
• Private, discreet service 
• No GP referral required 
• Expert guidance on correct test selection 

Important Advice for Patients

• Do not rely on symptoms alone 
• Avoid self-diagnosis 
• Test early if symptoms appear 
• Seek urgent care if symptoms worsen