PGT-A Explained: The New IVF Genetic Test Improving Success Rates
For couples considering IVF, every decision carries emotional and financial weight. One of the latest advancements is PGT-A (Preimplantation Genetic Testing for Aneuploidy) — a genetic test performed on embryos during IVF to select those with the best chance of success.
But before investing in IVF and PGT-A, which can cost £5,000–£8,000 or more per cycle, it’s vital to start with the basics: blood tests, semen analysis, and fertility MOTs. At Marylebone Diagnostic Centre, 73 Baker Street, W1U 6RD, we provide advanced fertility screening tests in London, giving couples clarity before making life-changing decisions.
What Is PGT-A?
- PGT-A involves analysing embryos created through IVF.
- A few cells are taken from each embryo to check for chromosomal abnormalities (aneuploidy).
- Embryos with the correct number of chromosomes are more likely to implant successfully and result in a healthy pregnancy.
Recent UK trials show that PGT-A can significantly improve outcomes, particularly for women aged 35-42, where success rates can rise from 52% to 72% when using tested embryos.
Why Blood and Semen Tests Should Come First
Before investing in IVF, embryo testing, or advanced fertility treatments, a comprehensive fertility check is essential. Many fertility problems can be detected with targeted blood tests, hormone profiling, and semen analysis — helping patients make informed decisions sooner.
At MDC, our fertility MOTs include:
For Women
- AMH (ovarian reserve)
- Hormone profile: FSH, LH, oestradiol, prolactin, thyroid
- Vitamin and mineral levels: vitamin D, B12, folate, iron
For Men
- Semen analysis (count, motility, morphology)
- Sperm photographs
- DNA fragmentation test
- Male hormone panel (testosterone, FSH, LH, prolactin, SHBG)
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By identifying hormonal imbalance, sperm quality issues, or vitamin deficiencies early, many couples may avoid unnecessary or premature IVF cycles.
Who Benefits Most from PGT-A?
- Women over 35 with declining egg quality
- Couples with recurrent miscarriages
- Patients with multiple failed IVF cycles
- Couples at risk of chromosomal conditions
For these groups, PGT-A can help reduce emotional strain and improve outcomes. However, it is not suitable for everyone, and initial fertility investigations are always recommended.
The Cost Factor
IVF treatment in London can cost several thousand pounds per cycle, and additional procedures such as PGT-A embryo testing may add thousands more to the overall price. Because of this, many patients now search for fertility checks before IVF or tests before IVF UK to better understand their health before committing to advanced treatment. Without a proper medical assessment, couples risk investing heavily in IVF when correctable issues – such as thyroid imbalance, hormonal disruption, vitamin deficiencies, or sperm DNA fragmentation – may be contributing to delays in conception.
A structured fertility assessment provides clarity before moving forward. Targeted blood tests, hormone profiling, and comprehensive semen analysis can help identify risks early, improve treatment planning, and reduce unnecessary emotional and financial pressure. For many London patients, understanding their fertility baseline first helps them enter the IVF pathway with stronger medical insight rather than uncertainty.
At Marylebone Diagnostic Centre, we support individuals and couples by acting as a fertility knowledge hub before IVF. Our focus is on providing clear information, evidence-based testing, and personalised health insights so patients can make informed decisions about whether IVF, embryo testing, or alternative medical support is the right next step. By addressing underlying health factors early, patients may avoid repeated cycles and approach fertility treatment with greater confidence.
That’s why at MDC we strongly advise:
Start with fertility bloods, hormone tests, and semen analysis first. Don’t know what to go for? chat with us via WhatsApp – 07495970109 or send us an email to info@marylebonelab.co.uk. We are here to support you and be part of this journey.
FAQs
Why Choose MDC?
- Advanced fertility screening tests London
- Same-day Appointment for many blood and semen tests
- Trusted Central London clinic at 73 Baker Street
- Clear, step-by-step guidance before IVF
At MDC, we ensure you don’t waste time or money on unnecessary treatments.
Take Action Now
Before spending thousands on IVF, book your Fertility MOT London at Marylebone Diagnostic Centre.
+44 7495 970109 | marylebonediagnosticcentre.com
