What Is PSA and Why Every Man Over 40 Should Know About It

PSA stands for Prostate-Specific Antigen — a protein made by the prostate gland, which can be measured through a simple blood test.

Small amounts of PSA in your blood are normal. However, higher-than-expected levels can be an early sign of:

  • Prostate inflammation (prostatitis)
  • Benign Prostatic Hyperplasia (BPH) – an enlarged prostate
  • Prostate cancer

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Why Is PSA Testing Important?

Prostate cancer is the most common cancer in men in the UK, especially over the age of 50.
It often has no symptoms in the early stages, which is why testing is key.

Early detection can make a life-saving difference, especially if caught before it spreads.

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What PSA Levels Mean

PSA Result (ng/mL)Possible Indication
0–4Generally normal for most men
4–10Possible enlarged prostate or inflammation
10+Further investigation often required

Important: PSA isn’t a cancer diagnosis on its own — it’s a screening tool. Elevated levels require follow-up or specialist referral, which we can arrange.

Who Should Get a PSA Test?

You should consider PSA testing if you are:

  • Over 40 (especially with family history of prostate cancer)
  • Experiencing frequent urination, especially at night
  • Having difficulty starting or stopping urine flow
  • Feeling pain in the lower back or pelvis
  • Wanting to take a proactive health approach

We recommend annual testing starting from age 45–50, or earlier if you’re in a high-risk group.

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What’s Involved in a PSA Test?

It’s a quick blood draw, done at our Baker Street clinic — no fasting or preparation needed.

Results are usually ready within 24–48 hours, with clinical notes explaining your numbers and next steps, if needed.

You can also combine PSA testing with our:

Private PSA Testing in Central London

We’re conveniently located on Baker Street, and see clients daily from:

  • Harley Street
  • Mayfair
  • Euston
  • Paddington
  • Kings Cross
Prostate Cancer PSA, PSA Screening at Marylebone Lab in London

No GP referral needed
Same-day slots often available
Results within 1–2 days

“I had no symptoms, but a friend suggested I test my PSA. It came back high, and I followed it up quickly. I’m so grateful I didn’t wait.”
– Michael, 54, Harley Street

FAQs – PSA Testing for Men

Is the PSA test painful?
No – it’s a quick blood test done by our experienced team.
Do I need to fast?
No fasting required.
How often should I check my PSA?
Once a year after age 45–50, or more often if you have a family history or symptoms.
What if my PSA is high?
We’ll guide you on the next steps — whether it’s a repeat test, referral, or follow-up with a urologist.

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No GP referral needed
Same-day appointments on Baker Street
Trusted by men across Marylebone, Mayfair, and Central London

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Read More

  1. NHS – PSA Test Overview
  2. Prostate Cancer UK – PSA Test Explained
  3. NICE Guidelines – Prostate Cancer Diagnosis
  4. American Cancer Society – PSA Blood Test Facts
  5. Patient.info – PSA Test Information