Thyroid Peroxidase Antibodies
Thyroid Peroxidase Antibodies (TPO antibodies) are autoantibodies directed against thyroid peroxidase,
an enzyme essential for the production of thyroid hormones. This enzyme plays a key role in the synthesis
of thyroxine (T4) and triiodothyronine (T3).
When the immune system produces antibodies against this enzyme, thyroid hormone production may gradually
become impaired. Testing for TPO antibodies helps detect autoimmune thyroid disease, particularly
Hashimoto’s thyroiditis.
- Price: £65
- Code: TPO
- TAT: 1 - 2 Working Days
- Sample Type: Blood
Clinical Significance
Elevated TPO antibody levels are commonly found in autoimmune thyroid conditions.
Hashimoto’s thyroiditis, the most common cause of hypothyroidism in many populations,
is strongly associated with TPO antibodies.
In Graves’ disease, another autoimmune thyroid disorder, TPO antibodies may also be present.
Detecting these antibodies helps confirm the autoimmune origin of thyroid dysfunction.
Who Might Benefit From This Test?
Individuals experiencing symptoms of hypothyroidism such as fatigue, weight gain, cold intolerance,
hair thinning, depression, or slowed metabolism may benefit from TPO antibody testing.
The test may also be used in patients with abnormal TSH results, unexplained infertility,
or a family history of autoimmune thyroid disease.
Sample Collection
A blood sample is collected by a healthcare professional. The procedure is quick,
routine, and generally well tolerated. The sample is analysed using laboratory
immunoassay techniques to measure antibody levels.
Understanding Your Results
A positive result suggests autoimmune activity affecting the thyroid gland.
High levels of TPO antibodies are strongly associated with Hashimoto’s thyroiditis.
However, some individuals may have antibodies without symptoms and may require
periodic monitoring of thyroid function.
FAQs
When will I receive my results?
Results are usually available within the stated turnaround time.
Should I discuss my results with a doctor?
Yes, results should always be reviewed with a qualified healthcare professional.
Why Choose Marylebone Diagnostic Centre?
Marylebone Diagnostic Centre provides accurate thyroid antibody testing through
accredited laboratories, ensuring reliable results within approximately 1–2 days.
Book Now
Book now at Marylebone Diagnostic Centre to complete your diagnostic tests and health parameters.
