Marylebone Parameters
Recurrent Miscarriage Testing
Clinical clarity for your reproductive journey. Specialized testing to identify treatable factors associated with recurrent miscarriage and support your future pregnancy planning. Recurrent miscarriage is commonly defined as three or more consecutive pregnancy losses, although investigation may sometimes be considered after two or more miscarriages depending on individual clinical circumstances and risk factors. Identifying possible underlying causes can help guide further clinical management and support future pregnancy planning. At Marylebone Diagnostic Centre, we offer two blood test profiles designed to investigate medical factors that may be associated with recurrent miscarriage. These profiles assess a range of autoimmune, hormonal, metabolic, and nutritional markers that may influence reproductive health and early pregnancy outcomes.
Choose your option
What's included
Preparation: Fasting required. This profile is designed to investigate some of the most common medical factors associated with recurrent miscarriage, including autoimmune conditions, thyroid dysfunction, metabolic health, and general haematological markers. A key component of this profile is screening for Antiphospholipid Syndrome, an autoimmune condition associated with abnormal blood clotting and recurrent pregnancy loss. The profile also evaluates thyroid function and general health markers that may influence fertility and early pregnancy outcomes. This targeted panel can help identify potentially treatable conditions that may affect implantation, placental development, or early pregnancy maintenance.
Antiphospholipid Antibody Screening
- Lupus Anticoagulant
- Anticardiolipin Antibodies (IgG & IgM)
- Beta-2 Glycoprotein I Antibodies (IgG & IgM)
Thyroid Function Tests
- Thyroid Stimulating Hormone (TSH)
- Free T4
- Thyroid Peroxidase Antibodies (TPO)
Metabolic & General Health
- HbA1c
- Full Blood Count (FBC)
When Should You Consider Testing?
- Pregnancy History: Two or more consecutive miscarriages, three or more first-trimester pregnancy losses, or one or more second-trimester miscarriages.
- Medical Background: Personal/family history of autoimmune disease, known thyroid disease or PCOS, or planning pregnancy following previous loss.
- Test Preparation: Fasting is required (8–12 hours recommended). Water is allowed before the test. Continue regular medication unless advised otherwise by your doctor.
Choosing the Right Profile
If you are unsure which profile is most appropriate, our clinical team can help guide you based on your medical history and testing requirements.
References
- NICE (NG126): Ectopic pregnancy and miscarriage diagnosis.
- NICE CKS: Recurrent miscarriage assessment.
- RCHT: Antiphospholipid antibody testing recommendations.
- RCOG (No. 17): Investigation of Recurrent Miscarriage.
- Cambridge University Hospitals: NHS patient information.
Frequently asked questions
When will I receive my results?
Should I discuss my results with a doctor?
