Procalcitonin
Procalcitonin is a peptide precursor of the hormone calcitonin and is produced in increased quantities during systemic bacterial infection. Under normal physiological conditions, procalcitonin levels in the bloodstream are very low. However, in the presence of significant bacterial infection or sepsis, levels can rise rapidly and substantially, making it a valuable biomarker in acute clinical settings. Unlike many inflammatory markers that rise in both bacterial and viral infections, procalcitonin demonstrates greater specificity for bacterial causes. This makes it particularly useful in distinguishing bacterial infections from viral illnesses or non-infectious inflammatory conditions.
- Price: £120
- Code: PCL
- TAT: 3 Working Days
- Sample Type: Blood
Clinical Significance
Procalcitonin testing is widely used in the assessment of suspected sepsis, severe bacterial pneumonia, bloodstream infection, and other systemic bacterial processes. Elevated levels may indicate the presence of invasive bacterial infection and can assist clinicians in making timely decisions regarding antibiotic initiation or escalation. In addition to diagnosis, serial procalcitonin measurements may be used to monitor response to antibiotic therapy and guide decisions on treatment duration. Declining levels often indicate effective infection control, while persistently elevated levels may suggest ongoing infection. Mild elevations may also occur in major trauma, surgery, or severe systemic inflammation, so results must always be interpreted in clinical context.
Who Might Benefit From This Test?
This test may be appropriate for individuals presenting with high fever, suspected sepsis, severe respiratory infection, or systemic inflammatory symptoms where bacterial infection is a concern. It may also be requested to monitor treatment response in hospital or outpatient settings. Clinicians may include procalcitonin testing alongside C-reactive protein (CRP), full blood count, and blood cultures when evaluating acute infection.
Sample Collection
A blood sample is obtained by a qualified healthcare professional. The procedure is quick and straightforward. Samples are processed in accredited laboratories to ensure precise and timely results.
Understanding Your Results
Results are interpreted in conjunction with clinical findings, imaging, and other laboratory markers. Significantly elevated levels may indicate severe bacterial infection or sepsis and require urgent medical attention. Lower or borderline levels may suggest mild infection or a non-bacterial cause. Because early identification of bacterial sepsis is critical, prompt interpretation and appropriate clinical follow-up are essential.
FAQs
When will I receive my results?
Results are usually available within the stated turnaround time.
Should I discuss my results with a doctor?
Yes, results should always be reviewed with a qualified healthcare professional.
Why Choose Marylebone Diagnostic Centre?
At Marylebone Diagnostic Centre, we provide rapid-access infection and inflammatory marker testing in a professional clinical environment. Our experienced team ensures efficient sample handling and analysis through accredited partner laboratories. With a turnaround time of 3 days, this test delivers timely insight to support urgent clinical decision-making.
Book Now
Book the Procalcitonin (PCL) test today for accurate assessment of bacterial infection and inflammatory response.
