Marylebone Parameters
The Helicobacter pylori (H. pylori) Antigen Stool Test is a non-invasive test used to detect the presence of H. pylori antigens in a stool sample. Antigens are substances produced by the bacterium itself, meaning this test helps identify an active H. pylori infection rather than past exposure. H. pylori is a common bacterium that lives in the stomach and is associated with conditions such as chronic gastritis, peptic ulcers, and, in some cases, an increased risk of stomach cancer. Because the stool antigen test detects current infection, it is particularly useful for diagnosis and for confirming whether treatment has been successful.
This test detects specific antigens from Helicobacter pylori present in the stool. Because antigens come directly from the bacteria, their presence indicates that H. pylori is currently living in the stomach.
Unlike antibody blood tests, which may remain positive long after infection has cleared, the stool antigen test reflects active infection. This makes it one of the most useful non-invasive tests for both diagnosing H. pylori and monitoring response to treatment.
This test may be recommended if you have symptoms such as persistent indigestion, upper abdominal pain, bloating, nausea, frequent heartburn, or a history of stomach or duodenal ulcers.
It is also commonly used after treatment for H. pylori to confirm that the infection has been successfully eradicated. Because of its accuracy for active infection, it is often preferred over blood antibody tests when checking treatment response.
A positive result indicates the presence of H. pylori antigens and confirms an active infection. A negative result suggests that H. pylori was not detected at the time of testing.
Results should be interpreted alongside symptoms and treatment history. Certain medications, such as antibiotics or acid-suppressing drugs, can affect results if taken close to the time of testing. Your healthcare professional will explain what your result means and whether any follow-up is required.
The test involves collecting a small stool sample at home using a provided collection container. Clear instructions are supplied to ensure accurate sampling and hygienic handling.
You may be advised to stop certain medications, such as antibiotics or proton pump inhibitors, before testing, as these can affect accuracy. No dietary preparation or fasting is required unless advised otherwise.

Marylebone Diagnostic Centre provides discreet and professional gastrointestinal testing with clear guidance, fast turnaround times, and supportive patient care.
Our experienced team ensures you understand how to collect your sample correctly and helps you interpret your results and next steps with confidence.
If you are investigating persistent stomach symptoms or confirming eradication after treatment, book your H. pylori Antigen (Stool) test with Marylebone Diagnostic Centre.
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