Marylebone Parameters
The Cyfra 21-1 blood test measures levels of cytokeratin 19 fragments circulating in the bloodstream. Cytokeratins are structural proteins found in epithelial cells, and Cyfra 21-1 is released into the blood when these cells break down. This marker is most commonly used in the monitoring of certain cancers, particularly those affecting the lungs.
Cyfra 21-1 is a tumour marker associated mainly with non-small cell lung cancer, although it may also be elevated in other malignancies or certain non-cancerous conditions. Tumour markers are substances that can be measured in the blood and may provide useful information about disease activity when used alongside clinical assessment and imaging.
It is important to understand that Cyfra 21-1 is not used as a screening test for cancer. Instead, it is most valuable for monitoring known conditions, assessing response to treatment, or supporting follow-up after therapy.
Your clinician may recommend a Cyfra 21-1 test if you are being monitored for a known lung condition or as part of follow-up after cancer treatment. Changes in Cyfra 21-1 levels over time can sometimes help indicate how a condition is responding to treatment.
Raised Cyfra 21-1 levels may be seen in certain cancers, particularly lung cancer, but they can also be affected by other medical conditions. For this reason, results are never interpreted in isolation. Your healthcare professional will consider trends over time, symptoms, imaging results, and other tests before explaining what your result means.
The test is performed using a simple blood sample taken during a short appointment. Our clinical team ensures the process is quick, professional, and as comfortable as possible.
No special preparation is required for this test.
Marylebone Diagnostic Centre provides high-quality laboratory testing with careful attention to accuracy, confidentiality, and patient care. We work with trusted laboratories and experienced clinicians to ensure reliable results and clear communication.
If you are monitoring a known condition or have been advised to check tumour marker levels, Marylebone Diagnostic Centre offers a reliable and professional service to support your care.
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