Health & Her Perimenopause Tablets: Side Effects Magnesium glycinate and when testing may help.
Feeling unwell after starting a supplement? Understand possible ingredient-related effects, how to avoid doubling up on magnesium, and whether a perimenopause test is useful.
Can perimenopause supplements cause side effects?
Yes. Vitamins, minerals and herbal ingredients can cause unwanted effects or interact with medicines. Feeling worse after starting a supplement should not automatically be dismissed as part of perimenopause.
Health & Her advises stopping its Perimenopause Multi-Nutrient Support product and seeking medical advice if you feel unwell.
This independent guide discusses possible effects of ingredients. It does not establish that this particular brand caused an individual’s symptoms or provide product-specific side-effect rates.
What is in Health & Her perimenopause tablets?
The standard UK Multi-Nutrient Support product reviewed for this article is supplied as capsules. Its ingredients include vitamins, magnesium citrate, iron, zinc and botanicals such as ashwagandha, red clover, sage and ginkgo.
It already contains magnesium
The manufacturer currently lists 56.3 mg of magnesium per daily serving, supplied as magnesium citrate. This is different from magnesium glycinate.
Different versions have different formulas
Gummies, capsules and other products in the range may differ. Check your own packaging before adding another supplement.
Product information checked on 1 October 2026. Formulations may change. Health & Her is a third-party brand; its mention here does not imply an affiliation with MDC.
What symptoms should you watch for?
Loose stools or stomach cramps
Supplemental magnesium can cause diarrhoea, nausea or cramping, particularly as the total dose increases. Taking several magnesium-containing products can add up.
Digestive upset or drowsiness
Ashwagandha can cause stomach upset, vomiting, diarrhoea or sleepiness in some people. Individual reactions vary between preparations and doses.
Medicine interactions
Ashwagandha may interact with medicines including sedatives, thyroid hormone and some diabetes treatments. Ask a pharmacist to check your full ingredient list.
When to seek urgent help
Call 999 for breathing difficulty, throat or tongue swelling, or collapse. Seek urgent medical assessment for yellow skin or eyes, dark urine, severe abdominal pain or persistent vomiting.
Rare liver injury has been reported with ashwagandha supplements generally. This does not establish a specific risk rate for the Health & Her product.
Is magnesium glycinate helpful during perimenopause?
Magnesium glycinate is magnesium bound to the amino acid glycine. Supplementation can help when magnesium intake or levels are inadequate, but it does not diagnose perimenopause or replace treatment for troublesome symptoms.
Is it proven to improve sleep?
Evidence for magnesium supplements as a treatment for insomnia is limited. Claims that glycinate reliably treats perimenopausal sleep problems or “balances hormones” go beyond established evidence.
Can I take it with a multinutrient?
Check the combined amount of elemental magnesium across all products first. The weight of a magnesium compound is not the same as the magnesium it provides.
Who needs extra advice?
People with kidney disease should seek advice before supplementing. Magnesium can also reduce absorption of some antibiotics and osteoporosis medicines; a pharmacist can advise on spacing.
Do I need a perimenopause test?
Not everyone does. NICE recommends identifying typical perimenopause clinically in otherwise healthy people aged 45 or over, using symptoms and menstrual changes.
Symptoms usually guide diagnosis
Routine hormone tests are generally unnecessary. A single normal hormone result does not rule out perimenopause because levels fluctuate.
FSH testing may be considered
A clinician may use follicle-stimulating hormone testing when menopause-associated symptoms include a change in the menstrual cycle.
Arrange a clinical assessment
Suspected premature ovarian insufficiency requires assessment. NICE recommends elevated FSH on two samples, four to six weeks apart, alongside the relevant clinical history.
Could something else explain the symptoms?
A clinician may investigate other causes of tiredness, palpitations or cycle changes. Testing should follow your history and symptoms, rather than automatically ordering a large panel.
Blood count and iron stores
These may be relevant when fatigue occurs with heavy periods or other reasons to suspect anaemia or iron deficiency.
Thyroid function
Thyroid problems can overlap with symptoms attributed to perimenopause. Testing may help when your clinical history suggests it.
Selected nutrient or electrolyte tests
These may be appropriate for specific symptoms, dietary risks, medicines or medical conditions. They are not a routine requirement for every supplement user.
No blood panel can certify that a herbal supplement is safe for you or rule out every interaction.
Support for your next step in London
Perimenopause Testing Information
Explore MDC’s perimenopause page and contact the team to discuss whether testing is appropriate for your age, symptoms and treatment.
Menopausal Profile
View MDC’s profile and confirm which tests are included. A hormone profile should not be treated as a definitive perimenopause diagnosis.
Women’s Health Testing
Explore services relevant to menstrual changes, hormones and other health concerns. Ask about arranging doctor review where needed.
Common questions
Should I keep taking a supplement if it makes me unwell?
No. Stop the suspected supplement and seek advice. Do not assume that symptoms mean it is “detoxing” your body or that you need to push through.
Can I take it alongside HRT?
Ask your pharmacist or prescriber to check the exact product and your medicines. Herbal ingredients and individual medical conditions matter; “natural” does not guarantee compatibility.
Do supplements replace menopause treatment?
No. If symptoms affect daily life, discuss established options such as HRT, where suitable, and menopause-specific cognitive behavioural therapy.
Should new bleeding be blamed on perimenopause?
Not automatically. Bleeding after 12 months without periods needs medical assessment, even if it happens only once. Heavy or unusual bleeding should also be discussed with a clinician.
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