Advanced Fertility & Preconception Genetic Testing
Fertility & genetics
Understanding the genetics behind fertility and future family health
Genetics can play an important role in both male infertility and the risk of passing certain inherited conditions to children. At Marylebone Diagnostic Centre (MDC), London, we offer advanced genetic testing for individuals and couples who want to investigate unexplained fertility problems, understand potential genetic causes of abnormal semen parameters, or assess their risk of passing inherited conditions to their future children.
IBgenSperm — Male Fertility Genetic Test
Analyses 426 genes associated with sperm production, to help investigate potential genetic causes of male infertility.
Y Chromosome Microdeletion Testing
Checks for missing sections of the Y chromosome that can interfere with sperm production in severe male-factor infertility.
Genetic Compatibility Test — Basic
A focused carrier screening panel covering a selected group of important inherited disorders.
Complete Genetic Compatibility Testing
A broader carrier screen investigating more than 600 hereditary conditions before conception or fertility treatment.
Extended Genetic Compatibility Testing
Our most extensive carrier screening option, investigating more than 3,000 hereditary disorders.
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Which test is right for me?
The most appropriate test depends on your clinical history, family history and fertility investigations. Testing should therefore be selected with appropriate clinical guidance where indicated.
| Your situation | Test to consider |
|---|---|
| Unexplained male infertility | IBgenSperm |
| Azoospermia | IBgenSperm + Y Chromosome Microdeletions |
| Severe oligozoospermia | IBgenSperm + Y Chromosome Microdeletions |
| Persistently abnormal semen analysis | IBgenSperm |
| Planning pregnancy and want carrier screening | GCT |
| Family history of an inherited condition | GCT + genetic counselling may be appropriate |
| Partners are biologically related | Comprehensive GCT should be considered |
| Planning IVF | GCT may be considered before treatment |
| Want broader preconception screening | Complete or Extended GCT |
| Want the broadest carrier screening option | Extended GCT, 3,000+ conditions |
Test Prices & Turnaround Times
| Test | Scope | Price | Estimated TAT |
|---|---|---|---|
| Y Chromosome Microdeletions | Targeted male fertility genetics | £399.00 | 21 days |
| IBgenSperm | 426 male fertility-associated genes | £1099.00 | 21 days |
| GCT Basic | Focused carrier screening | £699.00 | 31 days |
| Complete GCT | 600+ hereditary conditions | £1299.00 | 31 days |
| Extended GCT | 3,000+ hereditary conditions | £1599.00 | 31 days |
Turnaround times are estimates and may vary depending on the sample, laboratory requirements and whether additional investigation is required.
Genetic screening cannot eliminate all genetic or reproductive risk. A negative carrier screening result significantly reduces the likelihood of carrying the conditions investigated but does not exclude all genetic disorders. The clinical significance of genetic findings can vary and some results may require interpretation by an appropriately qualified clinician or genetic counsellor.
