Protein (Urine – 24 Hour Collection)
The 24-Hour Urine Protein test measures the total amount of protein excreted in the urine over a full 24-hour period. Under normal circumstances, healthy kidneys prevent significant amounts of protein from passing into the urine. When the kidney’s filtration barrier is damaged or compromised, protein may leak into the urine — a condition known as proteinuria. Unlike a single spot urine test, a 24-hour collection provides a more accurate assessment of total daily protein loss, making it particularly valuable in diagnosing and monitoring kidney disease.
- Price: £30
- Code: UPR
- TAT: 10 Working Days
- Sample Type: 24 Hour Urine
Clinical Significance
Persistent proteinuria is often an early indicator of kidney dysfunction and may be associated with conditions such as diabetic nephropathy, hypertension-related kidney damage, glomerulonephritis, or autoimmune disorders affecting renal filtration. Higher levels of protein loss may indicate more advanced kidney involvement. In some cases, temporary or mild proteinuria can occur due to fever, intense physical activity, dehydration, or acute illness. However, sustained elevation requires careful clinical evaluation to determine underlying cause and severity. This test is frequently used in the monitoring of chronic kidney disease (CKD), nephrotic syndrome, and systemic conditions such as lupus or vasculitis that may affect renal function.
Who Might Benefit From This Test?
This test may be appropriate for individuals with abnormal kidney function tests, swelling of the legs or face, foamy urine, high blood pressure, or diabetes. It may also be requested in pregnancy where pre-eclampsia is suspected. Patients with known kidney disease may require periodic 24-hour urine protein measurement to monitor disease progression and response to treatment.
Sample Collection
This test requires collection of all urine passed over a 24-hour period into a designated container provided by the clinic. Clear written instructions are supplied to ensure accurate collection. Proper adherence to collection guidance is essential for reliable results.
Understanding Your Results
Results are interpreted alongside blood tests such as creatinine, estimated glomerular filtration rate (eGFR), and electrolyte levels. Elevated 24-hour protein excretion may indicate glomerular damage or increased renal permeability. The degree of protein loss helps determine severity and guides further investigation or management. Because kidney function interacts closely with blood pressure, metabolic health, and systemic disease, interpretation considers the full clinical context rather than isolated values.
FAQs
When will I receive my results?
Results are usually available within the stated turnaround time.
Should I discuss my results with a doctor?
Yes, results should always be reviewed with a qualified healthcare professional.
Why Choose Marylebone Diagnostic Centre?
At Marylebone Diagnostic Centre, we provide comprehensive renal and metabolic testing in a professional clinical setting. Our experienced team offers clear collection instructions and efficient laboratory processing. With a turnaround time of 2 days, this test supports timely diagnosis and monitoring of kidney health.
Book Now
Book the Protein (Urine – 24 Hour Collection) (UPR) test today to support detailed assessment of your kidney function and overall health.
