Marylebone Parameters
The Helicobacter pylori (H. pylori) Antibodies blood test measures antibodies produced by the immune system in response to infection with H. pylori, a bacterium that colonises the stomach lining. H. pylori infection is common worldwide and is associated with chronic gastritis, peptic ulcer disease, and an increased risk of stomach cancer in some individuals. This specific test measures IgG antibodies, which help indicate the body’s immune response to H. pylori exposure. Different antibody types provide information about the timing and nature of infection and are often interpreted together with symptoms and other investigations.
Helicobacter pylori is a spiral-shaped bacterium that survives in the acidic environment of the stomach. It can damage the protective stomach lining, leading to inflammation and, over time, ulcer formation.
Many people with H. pylori infection have no symptoms, while others may experience indigestion, bloating, nausea, abdominal pain, or recurrent stomach ulcers. Identifying infection helps guide appropriate treatment and reduce long-term complications.
This test may be recommended if you have ongoing upper gastrointestinal symptoms such as persistent indigestion, burning stomach pain, nausea, bloating, or unexplained iron deficiency anaemia.
H. pylori antibody testing may also be used when investigating a history of ulcers, assessing previous exposure, or supporting diagnosis when other tests are not suitable or available.
Detection of IgG antibodies suggests exposure to H. pylori. Depending on the antibody type, results may indicate recent, ongoing, or past infection.
Antibody testing does not always distinguish between current and past infection on its own. Results are interpreted alongside symptoms and, where appropriate, other tests such as stool antigen or breath testing. Your healthcare professional will explain what your result means and whether treatment or further testing is needed.
The test is performed using a blood sample collected during a short appointment. The procedure is routine, and our clinical team will ensure you are comfortable throughout.
No special preparation or fasting is required for this test unless you have been advised otherwise.

Marylebone Diagnostic Centre provides professional gastrointestinal-related antibody testing in a calm and supportive environment, with clear communication and careful interpretation of results.
Our experienced clinical team supports you in understanding your results and deciding on appropriate next steps for your digestive health.
If you are experiencing ongoing stomach or digestive symptoms, book your H. pylori Antibodies (IgG) – Quantitative blood test with Marylebone Diagnostic Centre.
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