Painful Period Blood Test London
Severe Period Cramps? Heavy Bleeding? PMS That Feels Unmanageable?
Why Are My Periods So Painful?
Painful periods (dysmenorrhoea) can be caused by: Hormonal imbalance, High oestrogen or low progesterone, Inflammatory conditions, Thyroid dysfunction, Iron deficiency from heavy bleeding, Possible endometriosis or PCOS. Blood testing cannot diagnose endometriosis directly. However, it can identify patterns that require further investigation.
Many women are told: “Period pain is normal.” However, severe pain is not normal. If your period: Makes you cancel plans, Causes strong cramps, Leads to heavy bleeding or clots, Triggers mood swings, Makes you feel exhausted, Requires strong painkillers. You deserve answers.
At Marylebone Diagnostic Centre, we offer a comprehensive Painful Period Blood Panel in London to investigate hormonal imbalance, inflammation, thyroid dysfunction and nutrient depletion.
Severe period pain is not normal.
Clinical investigations for women who experience cycle pain that disrupts daily life.
What Does the Painful Period Blood Panel Include?
| Hormones | |
| Test | Why It Matters |
|---|---|
| FSH | Ovarian signalling |
| LH | Ovulation regulation |
| Oestradiol | Oestrogen balance |
| Progesterone | Luteal phase support |
| Prolactin | Can worsen PMS |
| Testosterone | Androgen excess / PCOS |
| SHBG | Hormone regulation balance |
| AMH | Ovarian reserve and fertility insight |
| Inflammation & Heavy Bleeding Markers | |
| Test | Purpose |
|---|---|
| CRP (High Sensitivity) | Detects inflammation |
| ESR | Chronic inflammatory marker |
| Full Blood Count | Anaemia detection |
| Ferritin | Iron storage levels |
Thyroid Function
Thyroid imbalance can worsen period pain and fatigue.
TSH | Free T4 | Free T3
Nutrient & Muscle Support
Vitamin D | Magnesium
Low levels may increase cramping and mood symptoms.
Painful Period Panel – Standard
- Hormones (FSH, LH, Oestradiol, Progesterone, Prolactin, Testosterone, SHBG)
- Inflammation & Anaemia (CRP - High Sensitivity, ESR, Full Blood Count, Ferritin)
Painful Period Panel – Advanced
- Hormones (FSH, LH, Oestradiol, Progesterone, Prolactin, Testosterone, SHBG)
- Inflammation & Anaemia (CRP - High Sensitivity, ESR, Full Blood Count, Ferritin)
- Thyroid Function (TSH, Free T4, Free T3)
Painful Period & Fertility Insight
- Hormones (FSH, LH, Oestradiol, Progesterone, Prolactin, Testosterone, SHBG, +AMH Fertility Insight)
- Inflammation & Anaemia (CRP - High Sensitivity, ESR, Full Blood Count, Ferritin)
- Thyroid Function (TSH, Free T4, Free T3)
- Nutrient & Muscle Support (Vitamin D, Magnesium)
Who Is This Test For?
This panel is suitable if you experience: Severe cramps every month, Pain radiating to back or legs, Heavy bleeding with clots, PMS mood changes, Nausea or fainting, Cycles affecting work or school, Difficulty conceiving. If symptoms are severe or worsening, further clinical review may be required.
When To Test?
For clinical accuracy, we recommend testing on:
- Day 2–5: Baseline hormones.
- Day 21: Progesterone/Ovulation check.
- Or as advised by our clinical team
Our team will guide you at booking.
Could This Be Endometriosis?
Endometriosis affects around 1 in 10 women. It is a complex condition that may cause:
Blood tests CANNOT confirm endometriosis. However, identifying inflammatory and hormonal patterns is the first step toward a diagnosis.
If patterns suggest further action, we can provide imaging referrals or specialist clinical review at a later stage.
Why Choose Marylebone Diagnostic Centre?
Frequently Asked Questions
Book Your Painful Period Blood Test in London
If your cycle affects your life, it deserves investigation. Book online today.
