Common causes include:

• Oxidative stress
• Smoking and alcohol
• Poor diet
• Heat exposure (e.g. laptops on lap, hot baths)
• Varicocele (enlarged veins in the scrotum)
• Infections or past fever
• Environmental toxins
• Ageing (especially over 40)

• <15% – Low fragmentation (good)
• 15–30% – Moderate (may affect fertility)
• >30% – High (linked to poor fertility outcomes)

Yes, but the chances of successful fertilisation, implantation, and healthy embryo development may be reduced if DNA damage is high.

A standard semen analysis checks sperm count, motility, and shape-but not DNA quality. A DNA Fragmentation Test goes deeper by examining the actual genetic health of sperm.

Absolutely. Many fertility clinics recommend it before assisted conception treatments, especially if there’s unexplained infertility or previous IVF failure.

Yes. Improvements in:

• Diet (high in antioxidants)
• Sleep
• Stress management
• Exercise
• Avoiding heat and toxins
  …can significantly lower DNA fragmentation over time.

Yes. Antioxidant supplements like vitamin C, vitamin E, CoQ10, zinc, and selenium may help reduce oxidative stress and improve sperm DNA integrity

We recommend waiting 3 months, as it takes that long for a full sperm production cycle to complete and reflect changes

It’s not routine for fertile men, but it’s valuable for those:

• Trying to conceive for 6–12+ months without success
• Over age 40
• Preparing for IVF/ICSI
• With history of miscarriage or lifestyle risk factors

Not at all. It only requires a semen sample, collected in a private, comfortable space at our clinic on Baker Street.

Very accurate. We use validated, laboratory-based assays designed to give clear, clinically useful results. It’s widely accepted by fertility specialist

Yes. We can arrange courier collection of the sample if you meet certain conditions, or we can support you with local collection at our Central London clinic.