Could NAD+ Be the Secret to A Healthier Heart?
New study reveals SIRT1 link to lower cholesterol & fewer heart attacks. When most people think of cholesterol or heart disease, they picture statins or diet plans. But cutting-edge research is now shining a spotlight on something far more intriguing: your cells’ natural longevity enzymes – and how NAD+ fuels them.
The exciting new science
A brand-new study has uncovered how SIRT1, an enzyme that relies on NAD+, might hold the key to better heart health. SIRT1 is known for its anti-ageing benefits, helping repair DNA, control inflammation, and keep metabolism in check. Normally, it lives inside your cells’ nuclei. But scientists found that SIRT1 also circulates in the blood, and remarkably, it can modify another protein called PCSK9.
Why does that matter? Because PCSK9 is a culprit in raising LDL cholesterol – the so-called “bad” cholesterol. When SIRT1 tweaks PCSK9, it encourages the liver to soak up more LDL, meaning less of it clogs your arteries.
In mice, this process reduced artery plaque. Even more compelling, humans with higher levels of circulating SIRT1 had fewer deaths from cardiovascular disease.
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What we’re seeing at Marylebone Diagnostic Centre
This ties beautifully into what we observe right here in Central London.
At Marylebone Diagnostic Centre, we routinely provide NAD+ IV therapy – known for supporting SIRT1 activity. We currently see five dedicated clients who come for NAD+ infusions three times a week, specifically to keep their energy and cardiovascular health in top form.
Two of these clients are over 55 yet remain remarkably fit and active. They credit NAD+ with helping them maintain vitality and resilience. It’s a small but fascinating snapshot that echoes what the latest research is telling us.
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Why this matters for you
This isn’t just about living longer – it’s about living better. Supporting your body’s NAD+ levels could activate key enzymes like SIRT1, potentially improving cholesterol handling, lowering plaque build-up, and protecting your heart. It might also boost energy, aid metabolism, and promote cellular repair – critical factors as we age.
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Considering NAD+ therapy?
Located on 73 Baker Street, just steps from Harley Street and Mayfair, Marylebone Diagnostic Centre offers bespoke NAD+ infusions in a calm, clinical environment. Our approach is fully personalised, with doctors and scientists who prioritise your long-term health.
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Ready to explore NAD+?
Whether you’re curious about longevity, heart health, or simply feeling more energised, our team is here to guide you.
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