Margaret & Menopause: Understanding Hormonal Change and Testing Options
By Dr Lauren Holland | Marylebone Diagnostic Centre, London
Across the UK, thousands of women – like Margaret, a busy professional balancing work, family, and wellbeing – are experiencing the profound changes of menopause.
While menopause is a natural stage of life, it often brings symptoms that affect physical, emotional, and mental health.
At Marylebone Diagnostic Centre (MDC), we help women take control of this transition with precise hormone testing and evidence-based support, offering reassurance and clarity through every stage.
What Happens During Menopause?
Menopause marks the end of menstrual cycles and typically occurs between ages 45–55.
It’s defined as 12 months after your last period, but hormonal changes begin years earlier during perimenopause.
Key hormone shifts include:
- Decline in oestrogen and progesterone, leading to irregular cycles and hot flushes.
- Fluctuations in FSH (Follicle-Stimulating Hormone), which signals ovarian decline.
- Changes in testosterone, affecting energy, libido, and mood.
Common Symptoms of Menopause
Every woman’s experience is unique, but common symptoms include:
- Hot flushes and night sweats
- Mood swings or irritability
- Fatigue or brain fog
- Sleep disturbance
- Low libido
- Weight gain, especially around the abdomen
- Joint pain or stiffness
- Hair thinning or dry skin
Understanding which hormones are changing – and by how much – is the first step to feeling better.
Hormone Tests Available at MDC
Female Hormone Profile
Measures oestrogen, progesterone, FSH, LH, and testosterone — giving a complete hormonal picture.
Thyroid Profile (TSH, FT4, FT3)
Thyroid disorders can mimic or worsen menopause symptoms such as fatigue and weight gain.
Vitamin D, B12 & Ferritin Levels
Nutrient deficiencies often amplify menopausal symptoms and reduce energy.
Cortisol & Stress Panel
Evaluates adrenal function – important because chronic stress can make hormonal symptoms worse.
All tests are performed with QC-validated accuracy, meeting the Marylebone High Standard for reliability and clinical precision.
Why Hormone Testing Helps
Testing gives women clarity and options.
It allows doctors to:
- Confirm menopause or perimenopause.
- Differentiate between hormonal and thyroid issues.
- Personalise treatment plans, including HRT if appropriate.
- Track improvements over time.
How MDC Supports Women Through Menopause
Our care model is designed around privacy, compassion, and science:
- Results within 24 – 42 hours.
- Doctor-led consultations to explain results clearly.
- Private suites for a comfortable, discreet experience.
- QC-validated laboratory testing under the Marylebone High Standard.
- Optional ongoing monitoring for hormone therapy or lifestyle changes.
Beyond Hormones: Menopause and Heart & Bone Health
Oestrogen decline affects more than mood – it also impacts cholesterol, bone density, and heart health.
That’s why many women over 45 benefit from:
MDC offers complete Well Woman and Menopause Profiles to cover these needs in one visit.
FAQs
Book Your Menopause & Hormone Health Profile Today
Take charge of your hormonal health today with expert, compassionate care at Marylebone Diagnostic Centre.
73 Baker Street, London W1U 6RD
+44 7495 970109
Monday–Saturday | 08:00 – 16:00
5-minute walk from Baker Street Tube
Results within 24 – 42 hours | QC validated | Tested to the Marylebone High Standard









