PGT-A Explained: The New IVF Genetic Test Improving Success Rates
For couples considering IVF, every decision carries emotional and financial weight. One of the latest advancements is PGT-A (Preimplantation Genetic Testing for Aneuploidy) — a genetic test performed on embryos during IVF to select those with the best chance of success.
But before investing in IVF and PGT-A, which can cost £5,000–£8,000 or more per cycle, it’s vital to start with the basics: blood tests, semen analysis, and fertility MOTs. At Marylebone Diagnostic Centre, 73 Baker Street, W1U 6RD, we provide advanced fertility screening tests in London, giving couples clarity before making life-changing decisions.
What Is PGT-A?
- PGT-A involves analysing embryos created through IVF.
- A few cells are taken from each embryo to check for chromosomal abnormalities (aneuploidy).
- Embryos with the correct number of chromosomes are more likely to implant successfully and result in a healthy pregnancy.
Recent UK trials show that PGT-A can significantly improve outcomes, particularly for women aged 35-42, where success rates can rise from 52% to 72% when using tested embryos.
Why Blood and Semen Tests Should Come First
Before investing in IVF and embryo testing, it’s essential to assess fertility health at the individual level. Many causes of infertility can be identified and treated with simple, cost-effective tests.
At MDC, our fertility MOTs include:
For Women
- AMH (ovarian reserve)
- Hormone profile: FSH, LH, oestradiol, prolactin, thyroid
- Vitamin and mineral levels: vitamin D, B12, folate, iron
For Men
- Semen analysis (count, motility, morphology)
- Sperm photographs
- DNA fragmentation test
- Male hormone panel (testosterone, FSH, LH, prolactin, SHBG)
Explore our Comprehensive Fertility Profiles.
By identifying hormonal imbalance, sperm quality issues, or vitamin deficiencies early, many couples may avoid unnecessary or premature IVF cycles.
Who Benefits Most from PGT-A?
- Women over 35 with declining egg quality
- Couples with recurrent miscarriages
- Patients with multiple failed IVF cycles
- Couples at risk of chromosomal conditions
For these groups, PGT-A can help reduce emotional strain and improve outcomes. However, it is not suitable for everyone, and initial fertility investigations are always recommended.
The Cost Factor
IVF is expensive, and PGT-A adds thousands of pounds per cycle. Without completing basic fertility health checks, couples risk spending money on advanced procedures when underlying, treatable issues (such as thyroid dysfunction or sperm DNA damage) may be the real barrier.
That’s why at MDC we strongly advise:
Start with fertility bloods, hormone tests, and semen analysis first.
FAQs
Why Choose MDC?
- Advanced fertility screening tests London
- Same-day Appointment for many blood and semen tests
- Trusted Central London clinic at 73 Baker Street
- Clear, step-by-step guidance before IVF
At MDC, we ensure you don’t waste time or money on unnecessary treatments.
Take Action Now
Before spending thousands on IVF, book your Fertility MOT London at Marylebone Diagnostic Centre.
+44 7495 970109 | marylebonediagnosticcentre.com
